Owen Wilson

Marmaduke (voice)

Emma Stone

Mazie (voice)

George López

Carlos (voice)

Caroline Sunshine

Barbara Winslow

Finley Jacobsen

Brian Winslow

Steve Coogan

Raisin (voice)

Christopher Mintz-Plasse

Giuseppe (voice)

Fergie

Jezebel (voice)

Kiefer Sutherland

Bosco (voice)

Lee Pace

Phil Winslow

Judy Greer

Debbie Winslow

Damon Wayans Jr.

Thunder (voice)