Robert Downey Jr.

Dr. John Dolittle

Harry Collett

Tommy Stubbins

Michael Sheen

Dr. Blair Müdfly

Jim Broadbent

Lord Thomas Badgley

Antonio Banderas

King Rassouli

Rami Malek

Chee-Chee (voice)

Jessie Buckley

Queen Victoria

Emma Thompson

Poly (voice)

John Cena

Yoshi (voice)

Kumail Nanjiani

Plimpton (voice)

Craig Robinson

Kevin (voice)

Ralph Fiennes

Barry (voice)