Bill Hader

Flint Lockwood (voice)

Anna Faris

Sam Sparks (voice)

James Caan

Tim Lockwood (voice)

Will Forte

Chester V (voice)

Andy Samberg

Brent McHale (voice)

Benjamin Bratt

Manny (voice)

Neil Patrick Harris

Steve (voice)

Terry Crews

Earl Devereaux (voice)

Kristen Schaal

Barb (voice)

Cody Cameron

Barry / Dill Pickle (voice)

Melissa Sturm

Sentinel Louise / Live Corp Scientist (voice)

Kris Pearn

Sentinel Peter / Labcoat Jenny (voice)