Rob Paulsen

Yakko Warner / Pinky / Dr. Otto Scratchansniff (voice)

Jess Harnell

Wakko Warner (voice)

Tress MacNeille

Dot Warner / Marita Hippo / Hello Nurse / Mindy's Mother (voice)

Maurice LaMarche

Brain / Squit (voice)

Nancy Cartwright

Mindy (voice)

Frank Welker

Various (voice)

Chick Vennera

Pesto (voice)

John Mariano

Bobby / Gas Station Attendant (voice)

Bernadette Peters

Rita (voice)

Sherri Stoner

Slappy Squirrel (voice)

Paxton Whitehead

King Salazar (voice)

Ben Stein

Desire Fulfillment Facilitator (voice)